18 May 2026Open access
Khellin-Derived Benzofuran–Pyrazoline Hybrids as Kinase-Targeted Anticancer AgentsPublisher siteACS Omega, Melanoma and MAPK Pathways
Active, last published 2026
In synthesis and biological activity
Samar H.
Fahim
Scholar“Research focused on Synthesis and biological activity and adjacent fields.”
Cairo University
Egypt
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01 · About the work
What I study
amar H. Fahim is a researcher working on Synthesis and biological activity. A fuller summary will appear once they update their profile.
02 · Reach
Publication output and reach
Samar's work has been cited 309 times across 5 active years. Bars show publications per year; the line shows cumulative citation totals across publications first appearing in each year.
03 · Research focus
Topics
Synthesis and biological activity×8Enzyme function and inhibition×6Synthesis and Catalytic Reactions×4Phenothiazines and Benzothiazines Synthesis and Activities×3Inflammatory mediators and NSAID effects×2
04 · Where I am
Affiliations
Affiliation on published researchCairo University, EgyptDrawn from the institution listed on this researcher’s published work.
Research themes (UN SDGs)
05 · Selected work
Recent publications
8 works11 May 2026Open access
A Box–Behnken design–assisted RP-HPLC method development and optimization for simultaneous determination of four antiviral drugs in pharmaceutical dosage formsPublisher siteScientific Reports, Analytical Chemistry and Chromatography
24 Sept 20252cites
Design, Synthesis, and 2D QSAR Analysis of Some Novel Pyrazolo[1,5‐a]pyrimidine Derivatives as Pim‐1 Kinase Inhibitors for the Treatment of MCF‐7 Breast CancerPublisher siteDrug Development Research, Cancer Mechanisms and Therapy
1 Jun 2025Open access7cites
Oxindole–Coumarin Hybrids With Broad‐Spectrum Anticancer Activity: Apoptosis Induction and Selective CA IX/XII TargetingPublisher siteDrug Development Research, Enzyme function and inhibition
20 Apr 2024Open access15cites
Probing benzenesulfonamide–thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase IIPublisher siteEuropean Journal of Medicinal Chemistry, Enzyme function and inhibition
2 Jan 2020Open access65cites
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluationPublisher siteEuropean Journal of Medicinal Chemistry, Enzyme function and inhibition
2 Nov 2019Open access55cites
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitorsPublisher siteEuropean Journal of Medicinal Chemistry, Enzyme function and inhibition
28 Jun 2019Open access27cites
Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IXPublisher siteEuropean Journal of Medicinal Chemistry, Enzyme function and inhibition
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