article · Access Microbiology

Whole genome sequencing and genotyping Klebsiella pneumoniae multi-drug resistant hospital isolates from Western Kenya

Victor Dinda
Daniel Kariuki
Anthony Wawire Sifuna
Martin Welch
Andrew Nyerere Kimang’a
Thomas O’Brien
Oleg N. Reva

20245 citationsOpen accessJomo Kenyatta University of Agriculture and Technology

Abstract

Our data suggest that the evolutionary success of ST147 may be linked with the acquisition of broad host-range plasmids, and their propensity to accrue AMR and virulence determinants. Although ST147 is a dominant lineage in many countries worldwide, it has not been previously reported as prevalent in Africa. Our data suggest an influx of new nosocomial pathogens with new virulence genes into African hospitals from other continents.

Research topics

Antibiotic Resistance in Bacteria
Bacterial Identification and Susceptibility Testing
Genomics and Phylogenetic Studies

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DOI: 10.1099/acmi.0.000667.v4

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