Vitamin D Deficiency in Hemodialysis Patients and Cardiovascular Diseases Risk

Abstract

Abstract Background Dialysis patients experience an excess mortality, predominantly of sudden cardiac death (SCD). Vitamin D deficiency is present in the vast majority of patients with chronic kidney disease (CKD), and correcting a poor vitamin D status is recommended as a treatment of CKD–mineral and bone disorders. Accumulating evidence suggests a role of vitamin D for myocardial and overall health. Aim of the Work To assess the correlation between vitamin D status and cardiovascular outcomes in prevalent hemodialysis patients. Subjects and Methods This was prospective interventional study, conducted Abo elnomros hemodialysis unit, on 50 prevalent HD patients. All patients were subjected to the following: Demographic data, laboratory investigations during the last 6 months, Echo-cardiogram before the study and after 6 months. Results The mean Ca was 7.94(±0.77 SD), the mean Po4 was 4.8(±0.8 SD), the mean PTH was 381(±127 SD), the mean vitamin D was 11.4(±1.5 SD). Conclusion High prevalence of vit D deficiency in dialysis patients, and showed a significant association between 25-OH vitamin D analogues supplementation and decrease cardio-vascular risk.