Verification of the analytical performance of the serum gamma-glutamyl transferase assay on the Abbott Alinity ci®: Experience of the biochemistry laboratory of the Mohammed VI university hospital of Oujda

Abstract

Introduction: As part of our study, we set out to evaluate the analytical performance of the gamma-glutamyl transferase (GGT) assay using an Abbott kit on the Alinity ci® automated system in the biochemistry laboratory of the CHU Mohammed VI in Oujda. Materials and methods: This study assessed the repeatability and reproducibility of Alinity ci® and compared the results obtained by the Alinity ci® and Architect ci-8200® automated systems. Results: The results obtained met the acceptability criteria recommended by the supplier and the Valtec protocol of the Société Française de Biologie Clinique (SFBC), demonstrating overall satisfaction with the study. The Alinity ci® automated system demonstrated the analytical performance required for accurate and reliable determination of GGT levels. Discussion: Validation of an analytical method is an essential step in guaranteeing that the result obtained is as close as possible to the reference value of a sample. Several standards and technical guides set out requirements for the performance criteria of an analytical method, notably NF EN ISO 15 189. Conclusion: the verification study of the GGT assay method produced satisfactory results, providing a high level of reliability for analysis results from the central laboratory of the CHU Mohammed VI d'Ouja. This work forms an essential basis for developing an accreditation procedure, which is part of the quality approach to which our laboratory is committed.