Verification of analytical performance of the aspartate aminotransferase assay on the Abbott Alinity ci®: Experience of the central laboratory Mohammed VI Oujda

Abstract

The standard NF EN ISO 15 189 mandates the verification of analytical methods. It involves evaluating an analytical method's effectiveness in accordance with a precisely laid out protocol before comparing it to previously established analytical objectives. Any biologist must be concerned with mastering this approach. In this work, we compare two automats: Alinity ci ® and Architect ci-8200® Abbott, to show the results of the protocol of verification of the method of determination of aspartate aminotransferase (AST). Aspartate aminotransferase is an enzyme found in many tissues, particularly liver and muscle, including heart muscle. Its measurement is particularly useful for diagnosing and monitoring liver disease.