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article · PLoS Medicine

Vaccination strategies to achieve outbreak control for MPXV Clade I with a one-time mass campaign in sub-Saharan Africa: A scenario-based modelling study

Abstract

With diminishing smallpox-vaccination-induced immunity, increasing disease transmissibility and potential for persistent outbreaks are expected for mpox, necessitating growing vaccine demand for outbreak containment. Given probable supply constraints, our findings could guide the ongoing and future mass vaccination efforts in sub-Saharan Africa by emphasising the prioritisation of high-risk groups, where allocation strategies are tailored to the evolving epidemiological landscape of each country.

Research topics

  • Poxvirus research and outbreaks
  • Bacillus and Francisella bacterial research
  • Animal Disease Management and Epidemiology

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DOI: 10.1371/journal.pmed.1004726

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