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article · Current Pharmaceutical Design

Unlocking the Enigmas of Plasmodium Aspartyl Protease in AntimalarialTherapy: Flap Region Dynamics and Enzyme Repression of Non-Food VacuoleUsing Molecular Dynamics Simulations

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Abstract

Finally, we developed a pharmacophore model based on UCB7362 to offer recommendations for rational drug design of optimized antimalarial drug candidates.

Research topics

  • Malaria Research and Control
  • Computational Drug Discovery Methods
  • Drug Transport and Resistance Mechanisms

Sustainable Development Goals

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DOI: 10.2174/0113816128288035240130102943

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