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article · Health Policy and Planning

Unfair knowledge practices in global health: a realist synthesis

202442 citationsOpen accessUniversity of the Witwatersrand

In plain language

Unfair knowledge practices often hinder health equity efforts between and within countries, typically enacted by powerful central actors over peripheral groups. A realist synthesis of literature from twelve journals systematises these practices by examining contexts, generative mechanisms, and outcomes. Four main categories of unfair knowledge practices emerged: credibility deficits related to pose, credibility deficits related to gaze, interpretive marginalisation related to pose, and interpretive marginalisation related to gaze. Each category is driven by three specific mechanisms reflecting assumptions about whose knowledge, standards, and priorities should govern collective knowledge production and interpretation. Furthermore, six overlapping contextual conditions shape these twelve mechanisms: mislabelling, miseducation, under-representation, compounded spoils, under-governance, and colonial mentality. This explanatory framework maps how institutional rationales and structural conditions perpetuate inequities in global health knowledge generation.

Key takeaways

  • Literature from twelve journals reveals that unfair knowledge practices stem from power imbalances between central and peripheral actors in global health.
  • Four categories of unfair practice involve credibility deficits and interpretive marginalisation linked to both pose and gaze.
  • Twelve distinct mechanisms drive these practices, rooted in dismissals of peripheral expertise and the prioritisation of central standards and learning needs.
  • Six structural contexts, including under-governance, mislabelling, and under-representation, reinforce the mechanisms of unfair knowledge production.
  • The findings provide a framework to inform ethics guidelines and future investigations into fairer research engagement.

Why it matters

Global health initiatives rely heavily on collaborative partnerships, but structural imbalances often silence local expertise. By clarifying the specific mechanisms and institutional rationales that discredit peripheral perspectives, this framework offers actionable insights for reforming research ethics guidelines, addressing power differentials, and fostering fairer knowledge creation between high-income institutions and the communities they study.

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Abstract

Unfair knowledge practices easily beset our efforts to achieve health equity within and between countries. Enacted by people from a distance and from a position of power ('the centre') on behalf of and alongside people with less power ('the periphery'), these unfair practices have generated a complex literature of complaints across various axes of inequity. We identified a sample of this literature from 12 journals and systematized it using the realist approach to explanation. We framed the outcome to be explained as 'manifestations of unfair knowledge practices'; their generative mechanisms as 'the reasoning of individuals or rationale of institutions'; and context that enable them as 'conditions that give knowledge practices their structure'. We identified four categories of unfair knowledge practices, each triggered by three mechanisms: (1) credibility deficit related to pose (mechanisms: 'the periphery's cultural knowledge, technical knowledge and "articulation" of knowledge do not matter'), (2) credibility deficit related to gaze (mechanisms: 'the centre's learning needs, knowledge platforms and scholarly standards must drive collective knowledge-making'), (3) interpretive marginalization related to pose (mechanisms: 'the periphery's sensemaking of partnerships, problems and social reality do not matter') and (4) interpretive marginalization related to gaze (mechanisms: 'the centre's learning needs, social sensitivities and status preservation must drive collective sensemaking'). Together, six mutually overlapping, reinforcing and dependent categories of context influence all 12 mechanisms: 'mislabelling' (the periphery as inferior), 'miseducation' (on structural origins of disadvantage), 'under-representation' (of the periphery on knowledge platforms), 'compounded spoils' (enjoyed by the centre), 'under-governance' (in making, changing, monitoring, enforcing and applying rules for fair engagement) and 'colonial mentality' (of/at the periphery). These context-mechanism-outcome linkages can inform efforts to redress unfair knowledge practices, investigations of unfair knowledge practices across disciplines and axes of inequity and ethics guidelines for health system research and practice when working at a social or physical distance.

Research topics

  • Global Health and Surgery
  • Viral Infections and Outbreaks Research
  • Global Maternal and Child Health

Sustainable Development Goals

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DOI: 10.1093/heapol/czae030

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