article · PLoS neglected tropical diseases

Transcriptome profiles of Trypanosoma brucei rhodesiense in Malawi reveal focus specific gene expression profiles associated with pathology

Peter Nambala
Harry Noyes
Enock Matovu
Janelisa Musaya
Annette MacLeod
Oscar A. Nyangiri
Vincent Pius Alibu
Joyce Namulondo
Barbara Nerima
Julius Mulindwa

2024Open accessMakerere University

Abstract

Our results suggest that the differences in disease presentation in the two foci is mainly driven by genetic differences in the parasites in the two major endemic foci of Rumphi and Nkhotakota rather than differences in the environment or host response.

Research topics

Trypanosoma species research and implications
Research on Leishmaniasis Studies
Insect symbiosis and bacterial influences

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DOI: 10.1371/journal.pntd.0011516

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