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article · Advances and Applications in Bioinformatics and Chemistry

Toward Understanding the Anticancer Activity of the Phytocompounds from Eugenia uniflora Using Molecular Docking, in silico Toxicity and Dynamics Studies

20241 citationOpen accessWalter Sisulu University

Abstract

This study has shown that polyphenol compounds of <i>E. uniflora</i> led by galloylastragalin, are potent inhibitors of the MDM2 and Bcl-xL cancer proteins. Thus, they may be considered as candidate polyphenols for further anticancer studies.

Research topics

  • Computational Drug Discovery Methods
  • Natural Antidiabetic Agents Studies
  • Phytochemistry and Biological Activities

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DOI: 10.2147/aabc.s473928

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