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article · Brain and Behavior

To Bridge or Not to Bridge? A Meta‐Analysis of Intravenous Thrombolysis Before Thrombectomy in Large Ischemic Core Strokes

2025Open accessAlexandria University

Abstract

In patients with large ischemic core infarcts, administering IVT prior to EVT does not confer significant clinical or procedural advantages over EVT alone. These findings underscore the need for further randomized controlled trials to inform optimal treatment approaches for this challenging patient population.

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DOI: 10.1002/brb3.71052

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