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article · Clinical and Experimental Pediatrics

Thyroid peroxidase gene variants and susceptibility to congenital hypothyroidism and autoimmune thyroid disease among Egyptian pediatric cohort

Abstract

These findings support a multifactorial model of pediatric thyroid disease, with the TPO Arg386His variant, particularly the His/His genotype, emerging as a key genetic contributor to disease susceptibility and severity.

Research topics

  • Thyroid Disorders and Treatments
  • Diabetes and associated disorders
  • Ophthalmology and Eye Disorders

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DOI: 10.3345/cep.2025.02957

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