article · African Health Sciences

The utility of Insulin Like Growth Factor Binding Proteins (IGFBPs-1, 2, 3) with genes expression in resistance to Imatinib and Nilotinib in chronic myeloid leukemia: a pilot study from Delta Egypt

Nadia El Menshawy
Shaimaa El‐Ashwah
Ramy Abbas
Maha Saif
Mostafa Abdelhakiem
Mohamed El-Ghonemy
Heidi Elkerdawy
Ahmed EL-Sebaie

2024Open accessMansoura University

Abstract

IGFBP-1 gene expression and its serum were significantly correlated with resistance. It is currently recommended that IGF-receptor inhibitors be developed and utilized. We are hoping to optimize the cure rate for CML treated with TKIs.

Research topics

Chronic Myeloid Leukemia Treatments

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.4314/ahs.v24i3.26

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