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article · Benha Journal of Applied Sciences

The Role Of MicroRNAs In Psoriasis Vulgaris

2024Open accessBenha University

Abstract

Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.Psoriasis is a skin condition that arises from immune cell dysregulation, aberrant neovascularization, and atypical activation of . After transcription, tiny noncoding RNAs called microRNAs mostly influence gene expression. New research reveals that microRNAs are essential in the development of and that their expression is impaired in people with the condition. There is currently a lack of knowledge about the precise roles and action mechanisms of miR-193b in the development of psoriasis. Furthermore, factor and the STAT3 and NF-κB signaling pathways are both inhibited by miR-193b.

Research topics

  • Dermatologic Treatments and Research
  • Urticaria and Related Conditions
  • Autoimmune Bullous Skin Diseases

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DOI: 10.21608/bjas.2024.328870.1522

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