article · PubMed

The preventive effects of diosmin alone or combined with irinotecan on 1,2-dimethylhydrazine-induced colon cancer in rats.

Mohamed Kaakoua
Abdelaziz S. A. Abuelsaad
M Abdelaziz
Ashraf Omar Abdelaziz
Hader I. Sakr
Osama M. Ahmed

20243 citationsBeni Suef University

Abstract

These findings suggest DIO, CPT-11, and their combination have anticarcinogenic effects against DMH-induced CC by suppressing oxidative stress, simulating the antioxidant defense system, attenuating the inflammatory effects, and reducing cell proliferation.

Research topics

Synthesis and biological activity

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DOI: 10.26355/eurrev_202407_36576

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