review · European Journal of Pain

The Efficacy and Safety of Botulinum Neurotoxin Type A in Treating Chronic Low Back Pain: A Systematic Review, Meta‐Analysis, Trial Sequential Analysis, and Meta‐Regression

Waseem Wagrees
Diana Greene‐Chandos
Abdelrahman Mahmoud
Mohammad Jadidi
Ahmed Naeem
Ahmed Abd Elazim
Yehya Khlidj
Arthur Kay
Hazem Mohamed Salamah
David P. Lerner
Hesham Kelani
Bahaa Sharaf
Moustafa Elnewishy
Lisa R. Merlin
N. Albaramony
Mohammad El‐Ghanem
Mohamed R. Abdelraouf
Charles Brock

20251 citationOpen accessAlexandria University

Abstract

This paper provides good evidence that BoNT-A may be employed in patients suffering from resistant chronic low back pain not responding to normal saline injection due to its higher efficacy and longer duration of action. Compared to steroids and local anaesthetics injections, there is not enough data to draw a firm conclusion and future studies are needed.

Research topics

Botulinum Toxin and Related Neurological Disorders
Musculoskeletal pain and rehabilitation
Myofascial pain diagnosis and treatment

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DOI: 10.1002/ejp.4796

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