The Clinicoepidemiological Features and Treatment Outcomes in Cervical Carcinoma at Clinical Oncology Department of Ain Shams University Hospital: Retrospective Analysis

Abstract

Abstract Background Through Increased education, access to care, and the expansion of screening and vaccination programs, reductions in cervical cancer incidence and mortality may be achieved. Aim and Objectives the aim of the study was to determine the clinicoepidemiological features and treatment outcome in cancer cervix at clinical oncology department of Ain Shams University Hospital. Subjects and Methods This retrospective analytical study included consecutive adult female patients ≥ 18 years with pathologically confirmed cervical cancer presented to the Clinical Oncology Department, Ain Shams Faculty of Medicine, Cairo, Egypt from January 2016 to December 2020. Results Most of the patients (71.3%) were under 60years, andthe median age at diagnosis was 53 years. In our cohort, about 54.5 % of patients were postmenopausal, with the median age of menopause around 51.0 years. In most cases, the age of menarche was between 9 and 12 years. 94.1.0 % of the patients were married, and most of them got married after reaching the age of 18 years (74.2%). In our cohort, CCRTH improved both DFS and OS for adjuvant groups as well as PFS and OS for patients who received definitive treatment. Univariate analysis including age, menopausal status, sociodemograhic data, tumor characteristsics, FIGO sataging and treatment received showed that significantrisk factors for reduced PFS and OS of patients who received palliative treatment was Diabetus mellitus as a comorbidity. Conclusion This data emphasizes that patient in rural setting present at later stages which could be improved by creating awareness in rural women, and help accessing adequate screening measures.