The changing scenario of infective endocarditis

Abstract

Almost invariably, articles dealing with the complex topic of infective endocarditis (IE) highlight in their introductory remarks that IE is an uncommon disease with a high mortality burden [1].The medical community thus recognizes that this is a serious and still challenging disease as mortality and frequent morbid events are the norm and not the exception [2].Looking at IE from any perspective, it seems that rough data with regard mortality, medical and surgical, has not substantially changed since the early reports on surgical treatment, pathophysiology, and chemotherapy [3,4].This introductory editorial focuses on discussing the evolution of the status of IE over time.