The antitumour efficacyof hesperidin vs. cisplatin againstnon‑small lung cancer cellsA549 and H460 via targetingthe miR‑34a/PD-L1/NF-κB signallingpathway

Abstract

Our study demonstrated that hesperidin extract could significantly inhibit non-small lung cancer cell growth by induction of the apoptosis signalling pathway. Therefore, hesperidin might open novel strategies for effective and safe cancer treatment and reduce the adverse side effects of several chemotherapeutic treatments such as cisplatin.