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article · PLoS neglected tropical diseases

Systemic inflammatory markers of visceral leishmaniasis treatment response in East Africa

2026Open accessMakerere University

Abstract

The recovery of haematological parameters, alongside a reduction in systemic inflammatory markers may be indicative of successful treatment of VL in East Africa. The biomarker dynamics suggest a partial resolution of inflammation and restoration of immune homeostasis during treatment. To confirm their predictive value, these markers should be evaluated in cohorts with a larger number of patients who experience treatment failure.

Research topics

  • Research on Leishmaniasis Studies
  • Macrophage Migration Inhibitory Factor
  • Cytokine Signaling Pathways and Interactions

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DOI: 10.1371/journal.pntd.0013749

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