article · New Journal of Chemistry

Synthesis, investigation of the crystal structure, DFT calculations, and <i>in silico</i> medicinal potential of hydrazono- and aminomethylene substituted pyrazolidine-3,5-diones as potential anticancer scaffolds

Youness El Bakri
Shaaban K. Mohamed
Rashad Al‐Salahi
Sabir Ali Siddique
Hatem A. Abuelizz
Joel T. Mague
Muhammad Sarfraz
Eman A. Ahmed

20243 citationsSohag University

Abstract

Two new pyrazolidine-3,5-dione derivatives were synthesized and their structures were elucidated by single-crystal X-ray analysis. The molecules were screened for their medicinal potential based on physiochemical and pharmacokinetics.

Research topics

Synthesis and biological activity
Bioactive Compounds and Antitumor Agents
Synthesis of heterocyclic compounds

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DOI: 10.1039/d4nj01839g

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