Synthesis, Characterization and Antimicrobial Activity of Mixed Ligand Metal (II) Complexes Derived from 2,2- Bipyridine and Oxalic Acid

Abstract

The synthesis of the metal (II) mixed ligand complexes of Mn, Co, Ni and Cu was carried out successfully by the reaction of the metal (II) chloride with the ligands 2,2-bipyridine and oxalic acid and characterized on the bases of solubility, decomposition temperatures, FTIR, UV-visible data, molar conductance, magnetic susceptibility, and elemental analysis. The analyses revealed that the metal complexes were soluble in DMSO, DMF and insoluble in certain organic solvents. It was discovered that the decomposition temperatures ranged from 243 - ˃300oC. The high decomposition temperature shows that the complexes are stable in nature. The IR data show that the mixed ligands were coordinated to each of the metal (II) ions. The non-electrolytic nature of all the complexes is indicated by their low molar conductance values (4.72-29.77 ohm-1 cm2 mol-1). Magnetic moment values (1.780-5.1085BM) of the complexes showed that all are paramagnetic in nature. The elemental analysis results of the ligands and the metal (II) complexes shows that the calculated percentages of C, H and N in the compounds and the experimental values(found) were in good agreement. This agrees with the proposed structures of the complexes. The antibacterial and antifungal activities of the ligands and metal (II) were carried out. The metal complexes exhibit moderate antibacterial and antifungal activities compared to the free ligands. Generally, the activity increases with increase in concentrations. But their activities are lower than that of the controls.