Sweet Syndrome Induced by AFINITOR: Case Report

Abstract

This is the most common neutrophilic dermatosis and the prototype of superficial dermal acute neutrophilic dermatoses. Its incidence is rare. Sweet's syndrome predilection is for adults aged 30 to 50, but children have also been reported. There is a female predilection [1]. It is distributed worldwide, with no racial predilection. The typical picture is of a sudden-onset rash, accompanied by high fever and neutrophilic leukocytosis [2]. Recombinant granulocyte-colony stimulating factor (G-CSF) has been implicated in almost half of all cases. All observations of G-CSF-induced Sweet syndrome have been reported in the course of hematological malignancies or HIV infection [3].