Strengthening regional laboratory networks and collaborative research on emerging pathogens: The role of the molecular research facility at Abubakar Tafawa Balewa University Teaching Hospital, Bauchi

Abstract

Introduction Emerging and re-emerging infectious diseases, particularly viral haemorrhagic fevers like Lassa fever, Ebola, and yellow fever, continue to challenge public health systems in West Africa. The COVID-19 pandemic caused significant global mortality but also advanced modern laboratory and clinical diagnostics, raising new research questions. The Molecular Genetics and Infectious Disease (MOGID) Research Laboratory at Abubakar Tafawa Balewa University Teaching Hospital (ATBUTH) in Bauchi, Nigeria, is an NCDC-optimized facility for RT-qPCR diagnostics of Lassa virus (LASV), SARS-CoV-2, Monkeypox (Mpox), and Varicella zoster virus (VZV). It serves Bauchi and neighbouring states including Borno, Gombe, Taraba, and Yobe. The laboratory plays a central role in surveillance, diagnostics, and outbreak response. To highlight the MOGID laboratory as a strategic centre for collaborative research and sustainable capacity building aimed at closing research and preparedness gaps for emerging and re-emerging pathogens in West Africa. Methods We conducted a descriptive assessment of the facility’s diagnostic capabilities, service coverage, and ongoing collaborations. Emphasis was placed on its integration with clinical services and potential for regional R&D partnerships. Results The state’s surveillance activities have positioned the laboratory as a central link for service delivery in patient care and treatment outcomes. Through ongoing support from donors and national stakeholders, the laboratory has developed a strong foundation for collaborative scientific research, workforce development, and operational readiness for public health threats. Conclusion There is a great opportunity for collaborative research, data sharing, and the exchange of resources and expertise with other institutions and countries. Such partnerships can address research gaps and help shape sustainable strategies for the prevention of disease emergence. Our participation in collaborative research efforts will contribute significantly to the regional infectious disease research agenda and enhance preparedness for future outbreaks.