MARATTO

article · RSC Advances

SnCl <sub>2</sub> -catalyzed Kabachnik–Fields synthesis of α-aminophosphonates with potent antioxidant activity

Abstract

the FRAP and CUPRAC assays, the results demonstrated that several of these compounds exhibit comparable or even superior reducing power to ascorbic acid, particularly at low concentrations. These findings underscore the potential of these α-aminophosphonates as promising antioxidant agents for future applications. ADME analysis predicts good oral bioavailability, limited brain and skin penetration, and potential CYP450 inhibition.

Research topics

  • Organophosphorus compounds synthesis
  • Bone health and treatments
  • Phosphorus compounds and reactions

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

DOI: 10.1039/d5ra06186e

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.