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article · JAMA Cardiology

Sex Differences in Diagnosis, Treatment, and Cardiovascular Outcomes in Homozygous Familial Hypercholesterolemia

202425 citationsOpen accessUniversity of the Witwatersrand

Abstract

In this cohort study of individuals with known HoFH, MI was higher in men compared with women yet age at diagnosis and at first ASCVD event were similar. These findings suggest that early diagnosis and treatment are important in attenuating the excessive cardiovascular risk in both sexes.

Research topics

  • Lipoproteins and Cardiovascular Health
  • Hormonal Regulation and Hypertension
  • Atherosclerosis and Cardiovascular Diseases

Sustainable Development Goals

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DOI: 10.1001/jamacardio.2023.5597

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