article · Pneumonia

Sex-dependent vulnerability for Wistar rats model following intranasal instillation with Klebsiella pneumoniae ATCC 43816 causing lobar pneumonia

Patrick Hervé Diboue Betote
Nnanga Nga
Rasmané Semdé
Rodrigue Fifen
Esther Del Florence Moni Ndedi
Sandrine Suzanne Bayengue Beack
Gabriel A. Agbor
R. Ouedraogo
Sonia Raïssa Gayap Matchuenkam
Maximilienne Ascension Nyegue

2024Open accessUniversité de Yaoundé I

Abstract

The results obtained highlighted the gender-dependency in the physiopathogenesis processes of K. pneumoniae ATCC 43816 induced-lobar pneumonia, in Wistar rats. Female Wistar rats' susceptibility is useful in studying pathology and in preclinical trial investigations of new treatments for infectious pneumonia.

Research topics

Pneumonia and Respiratory Infections
Immune Response and Inflammation
Antibiotic Resistance in Bacteria

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1186/s41479-024-00126-y

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