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article · PLoS ONE

Seroepidemiology of SARS-CoV-2 in a cohort of pregnant women and their infants in Uganda and Malawi

20242 citationsOpen accessMakerere University

Abstract

In total, 1379 women were enrolled, giving birth to 1387 infants. Overall, 63% of pregnant women had a SARS-CoV-2 positive serology. Over subsequent waves (delta and omicron), in the absence of vaccination, seropositivity rose from 20% to over 80%. The placental transfer GMR was 1.7, indicating active placental transfer of anti-spike IgG. There was no association between SARS-CoV-2 antibody positivity and adverse pregnancy or infancy outcomes.

Research topics

  • COVID-19 Impact on Reproduction
  • Vaccine Coverage and Hesitancy
  • Pregnancy and Medication Impact

Sustainable Development Goals

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DOI: 10.1371/journal.pone.0290913

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