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review · Antioxidants

Selenium Nanoparticles as a Natural Antioxidant and Metabolic Regulator in Aquaculture: A Review

2021143 citationsOpen accessKafr el-Sheikh University

In plain language

Balanced nutrition in aquafeed is critical for aquaculture productivity, yet standard plant and animal ingredients often fail to supply adequate minerals. Selenium serves as an essential trace element necessary for vital physiological processes, including antioxidant enzyme synthesis, immune system stimulation, and disease resilience. It also supports key metabolic functions such as thyroid hormone generation, cytokine formation, fecundity, and DNA synthesis. Nanotechnology advancements have enabled the manufacture of selenium nanoparticles, which offer greater solubility and bioavailability compared to traditional organic and inorganic sources. Numerous studies have assessed the influence of these nanoparticles on aquatic animal wellbeing and performance. Synthesising findings across recent investigations, this work outlines how selenium nanoparticles regulate metabolism and oxidation, providing a foundation for ongoing research and practical developments in aquafeed formulation.

Key takeaways

  • Standard ingredients in aquafeed do not provide sufficient mineral levels, necessitating precise supplementation based on species, age, and size.
  • Selenium is an essential trace element that strengthens antioxidant capacity, immune responses, and disease resistance in aquatic species.
  • Key biological processes, including thyroid hormone synthesis, cytokine production, fecundity, and DNA creation, depend on adequate selenium intake.
  • Selenium nanoparticles provide higher solubility and bioavailability than conventional organic or inorganic selenium sources.

Why it matters

Aquaculture productivity depends heavily on maintaining optimal animal health and growth through balanced feed. Traditional diets often lack critical trace elements, leaving farmed aquatic species susceptible to disease and oxidative stress. Utilising highly bioavailable selenium nanoparticles can enhance nutrient delivery, improve disease resistance, and support vital biological functions, ultimately helping producers sustain healthier stocks and improve overall yield.

Commercialisation angle

This research targets aquafeed manufacturers and aquaculture producers seeking enhanced mineral supplements. Selenium nanoparticles could be formulated into commercial diets to improve fish health and productivity. Because the work reviews existing research studies rather than presenting a scaled, ready-to-market product, the application remains in the research and development phase, requiring further testing to establish optimal dosing across specific commercial aquatic species and farming conditions.

AI-generated from the published abstract. Always read the original work before citing.

Abstract

Balanced aquafeed is the key factor for enhancing the productivity of aquatic animals. In this context, aquatic animals require optimal amounts of lipids, proteins, carbohydrates, vitamins, and minerals. The original plant and animals' ingredients in the basal diets are insufficient to provide aquafeed with suitable amounts of minerals. Concurrently, elements should be incorporated in aquafeed in optimal doses, which differ based on the basal diets' species, age, size, and composition. Selenium is one of the essential trace elements involved in various metabolic, biological, and physiological functions. Se acts as a precursor for antioxidative enzyme synthesis leading to high total antioxidative capacity. Further, Se can enhance the immune response and the tolerance of aquatic animals to infectious diseases. Several metabolic mechanisms, such as thyroid hormone production, cytokine formation, fecundity, and DNA synthesis, require sufficient Se addition. The recent progress in the nanotechnology industry is also applied in the production of Se nanoparticles. Indeed, Se nanoparticles are elaborated as more soluble and bioavailable than the organic and non-organic forms. In aquaculture, multiple investigations have elaborated the role of Se nanoparticles on the performances and wellbeing of aquatic animals. In this review, the outputs of recent studies associated with the role of Se nanoparticles on aquatic animals' performances were simplified and presented for more research and development.

Research topics

  • Selenium in Biological Systems
  • Mercury impact and mitigation studies
  • Moringa oleifera research and applications

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DOI: 10.3390/antiox10091364

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