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article · New England Journal of Medicine

Second-Line Antiretroviral Therapy for Children Living with HIV in Africa

202512 citationsOpen accessUniversity of Zimbabwe

Abstract

Second-line ART regimens including TAF-emtricitabine and dolutegravir were effective for children, with no evidence of safety concerns. Ritonavir-boosted darunavir was also effective. (Funded by the European and Developing Countries Clinical Trials Partnership and others; CHAPAS-4 ISRCTN Registry number, ISRCTN22964075.).

Research topics

  • HIV/AIDS Research and Interventions
  • HIV/AIDS drug development and treatment
  • HIV-related health complications and treatments

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DOI: 10.1056/nejmoa2404597

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