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article · European journal of medical research

Safety, efficacy, OCT-assessed vascular healing and angiographic outcomes of polymer-free versus biodegradable-polymer drug-eluting stents in patients undergoing percutaneous coronary intervention: a systematic review and meta-analysis

2026Open accessAlexandria University

Abstract

PF-DES were associated with comparable safety to BP-DES; however, it exhibited higher rates of target lesion revascularization and greater late lumen loss were observed. OCT-derived findings were heterogenous and should be interpreted cautiously. Further RCTs with standardized imaging protocols and longer follow-up are warranted.

Research topics

  • Coronary Interventions and Diagnostics
  • Peripheral Artery Disease Management
  • Cardiac and Coronary Surgery Techniques

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DOI: 10.1186/s40001-026-03999-5

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