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article · Vaccine

Rotasiil vaccine effectiveness against rotavirus-associated hospitalizations in the Democratic Republic of the Congo: comparison of multivariate logistic regression and inverse probability treatment weighting methods in a test-negative design

20251 citationOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

Rotasiil vaccination under conditions of routine use effectively reduces rotavirus-associated diarrhea hospitalizations among children, supporting the ongoing use of rotavirus vaccine. The IPTW VE estimate was more precise than multivariate logistic regression but the confidence intervals overlapped, suggesting that the resulting VE estimates are not statistically different and the methods are complementary.

Research topics

  • Viral gastroenteritis research and epidemiology
  • Probiotics and Fermented Foods
  • Infant Nutrition and Health

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DOI: 10.1016/j.vaccine.2025.127944

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