Role Of platelet-Rich Plasma in Treatment of Post COVID-19 Olfactory Dysfunction

Abstract

Background: COVID-19-related olfactory dysfunction is a serious problem that affect quality of life. With Limited effective therapies exist we discuss the role of platelet-Rich Plasma as a therapeutic agent for this problem.Aim of the study: Evaluation of effect of platelet-rich plasma in treatment of Post COVID-19 Olfactory DysfunctionPatients and methods: The study recruited 28 patients with Post COVID-19 olfactory Dysfunction (Anosmia / hyposmia / Cacosmia) From E.N.T outpatient clinic of Minya university hospital. patients received platelet-rich plasma only in form of injection in olfactory cleft.Results: The median of Butanol Threshold test before for patients was 3 (1.5 – 4) , The median of Butanol Threshold test after for patients was 3 (1.5 – 5) , There was highly statistically significant increase among butanol threshold test after treatment than butanol threshold test before treatment. Conclusions: In conclusion, our findings indicated that using of PRP significantly reduced the duration of anosmia in patients. Notably, A highly statistically significant increase in Butanol Threshold tests after treatment compared to before, underscoring the potential benefit of PRP in addressing olfactory dysfunction in Post COVID-19 patients.