article · Frontiers in Oncology

Regional, demographic, and temporal trends in psychoactive substance use-related mental disorder and cancer mortality in U.S. adults: a nationwide CDC WONDER analysis (1999–2020)

Asma Chaudhary
Sameena Khan
Ayesha Khalid
Aroosha Waheed
Arham Khalid
Mirha Imran Khan
Ibrahiem Azeem Ajaz
Aisha L Chaudhary
Muhammad Sarim Azad Khan
Mohammed Hammad Jaber Amin

2026Open accessAlzaiem Alazhari University

Abstract

Overall, AAMR plateaued after 2012, with the highest burden in NH American Indian/Alaska Natives, males, and rural Midwest residents, highlighting demographic and geographic disparities among individuals with concomitant cancer and psychoactive substance use-related mental disorders.

Research topics

Substance Abuse Treatment and Outcomes
Smoking Behavior and Cessation
Data-Driven Disease Surveillance

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.3389/fonc.2026.1753582

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