article · The Journal of Clinical Endocrinology & Metabolism

Regional Adiposity and Insulin Sensitivity—Interactions With Menopause and HIV in Middle-Aged Black African Women

Maphoko Masemola
André Pascal Kengne
Karl‐Heinz Storbeck
Fredrik Karpe
James Hawley
Amy E. Mendham
Tommy Olsson
Nigel J. Crowther
Clément Kufe
Shane A. Norris
Carmen Pheiffer
Tinashe Chikowore
Lisa K. Micklesfield
Julia H. Goedecke

20241 citationUniversity of the Witwatersrand

Abstract

Insulin sensitivity and beta-cell function were distinctively associated with aSAT and gSAT. While menopause did not influence these relationships, HIV had a significant effect on adipose tissue, characterized by variations in cell size distribution and transcript levels within the depots.

Research topics

HIV-related health complications and treatments
Adipokines, Inflammation, and Metabolic Diseases
Diabetes, Cardiovascular Risks, and Lipoproteins

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1210/clinem/dgae447

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