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article · Malaria Journal

Pyrethroid-resistant malaria vector Anopheles gambiae restored susceptibility after pre-exposure to piperonyl-butoxide: results from country-wide insecticide resistance monitoring in Tanzania, 2023

202413 citationsOpen accessUniversity of Dar es Salaam

Abstract

The evidence of widespread pyrethroid resistance of the major malaria vector justifies the decision made by the Tanzania National Malaria Control Programme to transition to PBO-based ITNs. Without this switch, the gains achieved in malaria control could be compromised. Equally important, the lack of full restoration to susceptibility observed in three sentinel districts upon pre-exposure to PBO merits close monitoring, as there could be other underlying resistance mechanisms besides oxidase metabolic resistance.

Research topics

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Insect Resistance and Genetics

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DOI: 10.1186/s12936-024-05211-7

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