article · RSC Advances

Pyrazole/pyrimidine derivatives endowed with azobenzenes as dual EGFR <sup>T790M</sup> and VEGFR-2 inhibitors: anticancer, docking, synthesis, design and ADMET assessments

Kurls E. Anwer
Felemban Athary Abdulhaleem M
Nour E. A. Abd El-Sattar
Tamer Nasr
Ahmed El-morsy
Khaled El-Adl
Mohammed Elmowafy
Mohamed A. Abdelgawad
Naglaa M. Ahmed

20261 citationOpen accessHeliopolis University

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Abstract

New pyrazole/pyrimidine derivatives endowed with azobenzenes were synthesized using microwave and traditional methods.

Research topics

Synthesis and biological activity
HER2/EGFR in Cancer Research
Fibroblast Growth Factor Research

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DOI: 10.1039/d5ra08997b

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