Pruritus in Psoriatic Patients: A Review Article

Abstract

Background: Psoriasis, a chronic skin condition, often accompanies distressing pruritus, impacting patients' quality of life. Understanding the pathogenesis of pruritus in psoriasis offers promising avenues in psoriasis treatment. Objective: This review aimed to comprehensively explore the epidemiology, pathogenesis, clinical characteristics, impact on patients' quality of life, and treatment options associated with pruritus in psoriasis. Methods: We searched Google Scholar, Science Direct, PubMed and other online databases for Psoriasis, Pruritus and Quality of life. The authors also reviewed references from pertinent literature, however only the most recent or comprehensive studies from 2012 to 2023 were included. Documents in languages other than English were disqualified due to lack of translation-related sources. Papers such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations that were not part of larger scientific studies were excluded. Conclusions: Pruritus is a prevalent and distressing symptom in psoriasis, affecting a majority of individuals with the condition.