article · Frontiers in Toxicology

Protective effects of Lagerstroemia speciosa against paracetamol-induced renal and testicular toxicity in rats via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms

Nagham E Elsheshtawy
Bayan Bokhari
Bodour S. Rajab
Shaymaa Rezk
Engy Risha
Ahmed Ateya
Ghadir Sindi
Fatma Mohamed Abdelhamid
Rehab M. Bagadood
Mohamed El‐Boshy

2026Open accessMansoura University

Abstract

Collectively, these findings demonstrate that EELS exerts notable nephroprotective and gonadoprotective effects comparable to NAC, largely through the attenuation of oxidative stress, inflammation, and apoptosis.

Research topics

Drug-Induced Hepatotoxicity and Protection
Chemotherapy-induced organ toxicity mitigation
Liver physiology and pathology

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DOI: 10.3389/ftox.2026.1751678

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