Profiling Plant–pathogen Interactions by Integrative Omics Tools Leads to Speed Breeding of CRISPR-edited Disease-tolerant Crops

Abstract

Profiling plant–pathogen interactions through integrative omics tools accelerates the breeding of CRISPR-edited disease-tolerant crops by providing a comprehensive analysis of resistance molecular mechanisms. By combining metabolomics, proteomics, transcriptomics, and genomics, researchers can identify key genetic factors and pathways associated with plant defense responses. This holistic approach facilitates the precise editing of target genes using CRISPR technology, enhancing crop resilience to specific pathogens. The integration of omics data, CRISPR technology and speed breeding allows for rapid identification of beneficial traits and their incorporation into breeding programs, significantly reducing the time needed to develop disease-resistant varieties. This strategy not only improves crop productivity and sustainability but also addresses challenges posed by emerging plant diseases in a timely manner.