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article · EMJ Gastroenterology

Primary Squamous Cell Carcinoma of the Gallbladder with Hepatic Invasion: A Case Report

2025Open accessMohammed V University

Abstract

Background: Primary squamous cell carcinoma (SCC) of the gallbladder is a rare, aggressive malignancy with poor prognosis. Case Presentation: The authors report the case of a 52-year-old woman who presented with cholestatic jaundice and was diagnosed with unresectable gallbladder SCC invading the liver. Despite palliative chemotherapy and haemostatic radiotherapy, her condition deteriorated, and she died 6 months after diagnosis. Conclusion: This case underscores the aggressive nature and limited treatment options of gallbladder SCC.

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DOI: 10.33590/emjgastroenterol/ehnm5377

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