article · Cureus

Preventive Antibiotic Use and Complications After Endoscopic Retrograde Cholangiopancreatography in Patients Hospitalized for Primary Sclerosing Cholangitis

Fidelis E Uwumiro
Nsikan N Akpabio
Victory Okpujie
Miracle Chinonso Okoro
Michael M Bojerenu
Hillary Alemenzohu
Tosin Ayantoyinbo
Osarumwense D. Ufuah
Solomon Anighoro
Ihunanya Kanu
Samuel Asogwa
R.A. Lawal

2024Open accessUniversity of Benin

Abstract

The use of antibiotic prophylaxis in hospitalizations with PSC was correlated with a significant reduction in the odds of post-ERCP pancreatitis. Antibiotic prophylaxis did not improve the odds of post-ERCP sepsis or cholangitis. Prophylactic use of antibiotics should be individualized, considering both their anti-infective benefits and potential impact on the biochemical markers of liver disease.

Research topics

Gallbladder and Bile Duct Disorders
Colorectal Cancer Screening and Detection
Pancreatic and Hepatic Oncology Research

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.7759/cureus.64429

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