article · Frontiers in Medicine
Objective This study aims to determine the prevalence of uncontrolled asthma and its associated factors among adult asthmatic patients attending hospitals in Burao, Somaliland, in 2025. Method A cross-sectional study was conducted at four hospitals from May 1 to June 15, 2025, among 363 adult asthma patients selected using systematic random sampling. Data were collected using a structured, interviewer-administered questionnaire. Asthma diagnosis was confirmed by spirometry performed within 3 months before enrollment, demonstrating reversible airflow obstruction. Descriptive statistics summarized the sample characteristics. Variables with p < 0.25 in bivariable analysis were entered into multivariable logistic regression. Model fit was assessed using the Hosmer-Lemeshow test ( p = 0.423), and multicollinearity was checked using the variance inflation factor (VIF < 2 for all variables). A p -value < 0.05 was considered statistically significant. Result Out of 382 adult asthma patients approached, 363 were included in the study, yielding a response rate of 98.4%. The mean age of participants was 47.6 ± 9.98 years, with 56.8% being male. Uncontrolled asthma was identified in 57.9% of the participants. Multivariable analysis revealed significant associations with poor medication adherence (AOR = 27.89; 95% CI: 7.75–100.30; p < 0.001), persistent asthma severity (AOR = 3.42; 95% CI: 1.27–9.23; p = 0.015), a family history of asthma (AOR = 27.51; 95% CI: 2.51–301.60; p < 0.001), biomass fuel use (AOR = 8.56; 95% CI: 3.08–23.78; p < 0.001), and occupational dust exposure (AOR = 68.65; 95% CI: 3.80–1239.19; p = 0.004). Due to small cell counts for dust exposure ( n = 40 exposed) and family history ( n = 113 with family history, including only 1 well-controlled case), these estimates have wide confidence intervals and should be interpreted cautiously. Exact logistic regression was performed as a sensitivity analysis, which confirmed the direction and statistical significance of these associations. The presence of air conditioning was also associated with increased odds (AOR = 6.26; 95% CI: 1.44–27.21; p = 0.014). Good asthma knowledge approached significance as a protective factor (AOR = 0.45; 95% CI: 0.20–1.04; p = 0.060). Conclusion The burden of uncontrolled asthma in Burao City is high, with modifiable factors such as medication adherence and follow-up care playing a vital role. Targeted interventions addressing these factors are crucial to improving asthma control in this setting.
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DOI: 10.3389/fmed.2026.1823549
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