article · BMC Public Health
BACKGROUND: People with epilepsy suffer from recurrent attacks of uncontrolled seizures and their complications. People with epilepsy have experienced uncontrolled seizures worldwide. Poorly controlled seizures result in several health consequences. Therefore, this study aimed to assess the prevalence and determinants of uncontrolled seizures among adult people with epilepsy. METHODS: A multicenter, institutional-based, cross-sectional study was conducted from April 1, 2023, to April 30, 2023. A simple random sampling technique was used to select the study participants. The data were collected by using a structured, interview-administered questionnaire and a checklist filled out by observing the patients' charts. The data was entered by using Epi data version 4.6.02 software, then exported, coded, and analyzed using the Statistical Package for Social Science (SPSS) version 25. Hosmer Lemeshow model fitness and multi-collinearity by variance inflation factor were checked. Binary logistic regression with Adjusted Odds Ratio (AOR) with 95% CI was estimated, and a P-value < 0.05 was considered statistically significant. RESULTS: The overall prevalence of uncontrolled seizures was 172(42.6%). People with epilepsy who were unable to read and write [AOR = 5.13; 95% CI (1.55, 16.93)], had primary school [AOR = 5.73; 95% CI (1.89,17.42)], lived in rural residences [AOR = 1.99; 95% CI (1.03, 3.85)], had negative medication belief [AOR = 1.90; 95% CI (1.04,3.49)], take antiseizure medication for less than two years [AOR = 0.38; 95% CI (0.18,0.78)], and being farmer [AOR = 2.79; 95% CI (1.26, 6.19)], employment status [AOR = 0.13; 95% CI (0.04, 0.42)] was a significant association with uncontrolled seizure at p-value less 0.05. CONCLUSION: In this study, the prevalence of uncontrolled seizures among adults with epilepsy was higher than in previous studies. Educational status, residence, belief in antiseizure medication, duration of antiseizure medication, occupational status, and type of seizure were significant predictors of uncontrolled seizures.
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DOI: 10.1186/s12889-025-23922-7
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