Predictors of patient-perceived functional improvement after cardiac resynchronization therapy: a real-world multi-dimensional analysis of clinical, imaging, and ECG predictors

Abstract

Functional improvement after CRT is best predicted by multi-dimensional assessment incorporating clinical, biochemical, and imaging parameters. In addition to the traditional response definitions, renal function, LV GLS, and LV diastolic indices were independently associated with a better patient-perceived functional improvement after CRT. Incorporating these factors into CRT eligibility and prognostication may enhance patient selection and improve outcomes.