article · The Journal of Infectious Diseases

Pre–Human Immunodeficiency Virus (HIV) α4β7hi CD4+ T Cells and HIV Risk Among Heterosexual Individuals in Africa

Tosin Omole
Katherine K. Thomas
James G. Kublin
Nelly Mugo
Myo Minn Oo
Aida Sivro
Aloysious Ssemaganda
Giulia Severini
Lawrence Corey
Agata Marcinow
Jairam R. Lingappa
Andrew Mujugira
Connie Celum
Huong Nguyen
Glenda Gray
Naima Jahan
Lyle R. McKinnon

20243 citationsOpen accessUniversity of Nairobi

Abstract

These findings suggest that α4β7hi expression on CD4+ T cells may not predict HIV acquisition and progression in all contexts, which may be due to cohort effects, modes of transmission, viral clade, or other factors.

Research topics

HIV Research and Treatment
HIV/AIDS Research and Interventions
HIV, Drug Use, Sexual Risk

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1093/infdis/jiae638

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