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article · Malaria Journal

Plasmodium falciparum multidrug resistance 1 gene polymorphisms associated with outcomes after anti-malarial treatment

20254 citationsOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

These results support prior studies that suggested: (1) patients given AL and infected with parasites carrying N86 were more likely to experience a recurrent infection; (2) patients given ASAQ and infected with parasites carrying 86Y were more likely to experience a recurrent infection. These findings suggest that ACT and Pfmdr1 genotype may influence outcome after Plasmodium falciparum infection.

Research topics

  • Malaria Research and Control
  • Drug Transport and Resistance Mechanisms
  • Computational Drug Discovery Methods

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DOI: 10.1186/s12936-025-05248-2

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