article · Malaria Journal

Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo

Robert Verity
Jeffrey A. Bailey
Stephanie M. Doctor
Antoinette Tshefu
Oliver J. Watson
Jaymin C. Patel
Nicholas J. Hathaway
Andreea Waltmann
Kashamuka Mwandagalirwa
Jonathan J. Juliano
Azra C. Ghani
Steven R. Meshnick

201817 citationsOpen accessUniversité de Kinshasa (UNIKIN)

Abstract

Results suggest that the DRC fits within the global pattern of high var2csa diversity and little genetic differentiation between regions. A broad multivalent VAR2CSA vaccine candidate could benefit from targeting stable regions and common variants to address the substantial genetic diversity.

Research topics

Malaria Research and Control
Mosquito-borne diseases and control
Complement system in diseases

Sustainable Development Goals

11Sustainable Cities and Communities

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DOI: 10.1186/s12936-018-2193-9

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