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article · Acta Neuropsychiatrica

Placebo and Nocebo Effects of Pharmacotherapy for Obsessive-Compulsive Related Disorders: A Systematic Review and Meta-Analysis

Abstract

Placebo and nocebo responses are noteworthy in trials for OCRDs and may influence perceived treatment efficacy. Variability in placebo responses is not well explained by currently measurable moderators. Further research is needed to explore neurobiological, psychological, and methodological contributors to expectancy effects in OCRD pharmacotherapy trials.

Research topics

  • Obsessive-Compulsive Spectrum Disorders
  • Pain Management and Placebo Effect
  • Personality Disorders and Psychopathology

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DOI: 10.1017/neu.2026.10070

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