Phytochemical Constituents and in-vivo Immunomodulatory Role of Sclerocarya Birrea in Benzene Induced Leukemia Mouse Model

Abstract

Pharmacological exploitation of natural compounds has lead to the development of non-synthetic and nontoxic agents that are promising at ameliorating the menace of neoplastic diseases such as leukemia.The aim of this study was to determine the phytochemical and anti-leukemic effect of Sclerocarya birrea bark (Met.S.b) methanol extract on biomarker in benzene induced leukemia mice.Leukemia was induced in mice by intravenous injection of 0.2 mL benzene solution 48 hourly for 4 weeks.Methanolic extract of Sclerocarya